If you're scared, go to church.
Seriously though, Runemate itself is not detected. I'm convinced my bans are the result of players who have a vendetta against bots and just want to see the world burn. While I have botted on my main (1900+ skill), I never afk bot on that account. I've also invested quite a bit of hand playing on that account recently, so I'm sure that helps skew any of Jagex's heuristic detection methods. Also responding to players who are talking helps prevent them from just reporting you for botting for the hell of it.
With a free Runemate account and a new Runescape account, you can test out bots until you feel comfortable botting on your main. Just don't dive head first into botting on your main if it being banned will cause tears.