Hey, Wifty. Sorry you're having trouble with your computer. The language and tone that you are using certainly makes one wonder if you came here to be hateful or if you genuinely came here looking for help. Either way, no one here is attacking you.
If anyone here seems hesitant to give you the benefit of the doubt that Runemate ruined your computer, you'll have to forgive us because it's completely unheard of and many of us run this software daily. You said you uninstalled Runemate so it can't affect your PC, at least not directly. (see below) If you're implying that RM has some type of malware in it, a scan with any antivirus or malware software will show otherwise. Also, Runemate doesn't take over your mouse or keyboard even when it is running. It simply sends keyboard and mouse events to the Runescape software.
So here's what help I can offer:
Installs and uninstalls, especially rapid ones without restarts in between or multiple ones at the same time, can make unstable changes to the registry. Sometimes these things screw your computer up in various ways. Before doing anything else, go find a regsitry cleaner software and run it. Always back up your registry before making any changes to it. I'm willing to bet this will help. If it does not and you have ruled out some kind of malware attacking your computer, then you should consider a reset to factory settings. This is always an option with any OS and has subsequently gotten easier with each Windows version. Good luck and sorry you're having trouble. I hope you figure it out and come back. This is quite an awesome community.