On that front, very true - they wouldn't. But it's a very notable (who miss clicks that often - 3-5 times - on a simple task, every time), rapid (faster than a human would approach said task) and repeated (this occurs almost every time you want to drop or deposit something) action - so I'm assuming these would be big red flags.
That said, really impressed with the Prime Fishing bot - despite this issue it's performing really well on my test account, hopefully once Runemate fix this issue it'll be sweet sailing.